Personal Profile
| Name | Dr. Piya Ghosh |
| Designation | SACT |
| Department | Microbiology |
| Email Id | piyapc@gmail.com |
| Year of Joining present service | 2020 |
| Date of Appointment SACT | 01-01-2020 |
Educational Qualifications
| Passout Year | Examination | Passout From | Division |
|---|---|---|---|
| 2019 | Research Associateship | Biophysics Department, Bose Institute (as CSIR-RA from 2017 to 2019) | |
| 2017 | Postdoctoral Research | Biophysics Department, Bose Institute (as Institute Research Associate from 2016 to 2017) | |
| 2016 | Ph.D. | University of Calcutta (Ph.D done under supervision of Prof. Siddhartha Roy, Ex-Director, Indian Institute of Chemical Biology, Kolkata) | |
| 2007 | Master of Science (M.Sc.) | University of Calcutta (M.Sc in Biochemistry) | 1st CLASS |
| 2005 | Bachelor of Science (B.Sc.) | University of Calcutta (Chemistry Honours, Presidency College) | 1st CLASS |
College Served
| College Name | Served From | Served Till |
|---|---|---|
| Lady Brabourne College | Jan, 2020 | Mar, 2026 |
Area of Research and Interest
| Details |
|---|
| Biochemistry (Biomolecules, Enzymology, Bioenergetics and Metabolism), Cell Biology, Molecular Biology, Biophysics, Virology (Teaching) |
| Peptide Synthesis and Protein Purification, Cancer Biology and Application & Characterization of Bioremedial Microorganisms (Research) |
| Ph.D Research: Development of peptidomimetics (branched dimeric peptides) to inhibit protein-protein interactions in signaling pathways de-regulated in cancer, particularly malignant melanoma cells and to develop and test peptides which specifically target to cancerous tumors and/or blood vessels associated with the tumors in syngenic mouse melanoma model. |
| Post-Doctoral Research: As Extended Senior Research Fellow (Institute) from July, 2015 to January, 2016 and as Research Associate (Institute) from February, 2016 to May, 2017 in Department of Biophysics, Bose Institute on “Development of Synthetic Transcription Factors against pluripotency to Target Cancer Stem Cells” and as CSIR-Reseach Associate from June, 2017 till May, 2019, on “Understanding Molecular Basis of Drug Resistance Induced by Mutant p53” under the supervision of Prof. Siddhartha Roy. |
| Current Area of Research: 1. Assessing biological pollution markers and the effects of climate change in Sundarban Biosphere Reserve by enumeration, isolation and characterization of microorganisms exhibiting bioremedial properties like heavy metal leaching from soil, petroleum degradation and azo-dye degradation in soil under saline stress respectively. 2. Characterization of proteolytic enzymes from soil microorganisms for application in waste management. |
Publication: Research Papers in Journals
| Sl No. | Year/Month | Title | Name of Journal | Volume / Page No. |
|---|---|---|---|---|
| 1 | 2023 | Study of nano-hydroxyapatite tagged alkaline protease isolated from Himalayan sub-alpine Forest soil bacteria and role in recalcitrant feather waste degradation | International Journal of Biological Macromolecules (Elsevier) | 253, 127317 |
| 2 | 2018 | Mutant and Wild-Type Tumor Suppresor p53 Induces p300 Autoacetylation | iScience (Cell Press) | 2018; 4, 260-272 |
| 3 | 2018 | Constrained alpha-helical peptides as inhibitors of Protein-Protein and Protein-DNA interactions | Biomedicines (MDPI) | 6, 118 |
| 4 | 2018 | A Peptide-based Synthetic Transcription Factor Selectively Activates Transcription in a Mammalian Cell | Chemical Communications (Camb) (Royal Society of Chemistry) | 54, 1611-1614 |
| 5 | 2014 | Simultaneous Inhibition of Key Growth Pathways in Melanoma Cells and Tumor Regression by a Designed Bidentate Constrained Helical Peptide | Peptide Science (Wiley Periodicals, LLC) | 101(4), 344-358 |
| 6 | 2012 | Peptide based Molecules as Protein-Protein Interaction Inhibitors: Tools for Chemical Genetics and Therapy | Current Chemical Biology (Bentham Science Publisher) | 6(2), 145-163 |
Publication: Chapters in books
| Sl No. | Year/Month | Book Title | Chapter Title | Editor/Author | ISBN No. |
|---|---|---|---|---|---|
| 1 | 2020 | Protein–Protein Interaction Regulators (Publisher: Royal Society of Chemistry.) | “Helix-mimetics as Protein–Protein Interaction Inhibitors”, Chapter 7 DOI: 10.1039/9781788016544-00147 (Authors: Gitashri Naiya, Madhumita Chakraborty, Piya Ghosh, Siddhartha Roy) | Siddhartha Roy and Haian Fu | ISBN (Print) 978-1-78801-187-7 |
Pre-Publication Review
| Sl No. | Publication Details |
|---|---|
| 1 | Kaypee, Stephanie; Ghosh, Raka ; Sahadevan, Smitha; Patil, Shilpa; Shasmal, Manidip; Ghosh, Piya; Roy, Neeladri; Sengupta, Jayati; Roy, Siddhartha; Kundu, Tapas. (2018). The Wild-type and Gain-of-function Mutant p53 Enhance p300 Autoacetylation through Conformational Switching. 10.1101/194704. (bioRxiv pre-print) |
Talk/Lectures
| Sl No. | Date | Title | Organised By |
|---|---|---|---|
| 1 | 27-06-2024 | Invited lecture on "Food for Gut: Prebiotics, Probiotics and the Gut Microbiome" to celebrate World Microbiome Day | School of Life Sciences, Swami Vivekananda University, Barrackpore |
| 2 | 01-03-2017 | Invited lecture and demonstration on "Handling of HPLC" in Department of Higher Education, Science and Technology and Biotechnology, Government of West Bengal sponsored Two-day DBT-BOOST Workshop on “Analytical Techniques in Biotechnology: HPLC and Lyophilizer” | Department of Microbiology, Lady Brabourne College and sponsored by DBT-BOOST, West Bengal |
Oral/Poster Presentation
| Sl No. | Date | Title | Title of Conference | Organised By |
|---|---|---|---|---|
| 1 | 05-04-2024 | Screening of Potent Bioremedial Microorganisms from Soil of Sundarban Mangrove Region for a Sustainable Approach to Remove Hazardous Pollutants (Poster) | ‘International Conference on Scope of Microbiology Beyond Academia: Industry, Entrepreneurship and More’ | Dept. of Microbiology, Vijaygarh Jyotish Ray College in collaboration with Microbiologist Society of India & E-YUVA Centre, Adamas University |
| 2 | 23-03-2024 | Unearthing nature’s guardians of Sundarban mangrove regions | 2nd Botanical Congress 2024: National Seminar and Scientific Activities on ‘Plant Science, Biotechnology and Society’ | Dept. of Botany & Param Nath Bhaduri Crop Research and Seed Multiplication Farm, The University of Burdwan in collaboration with Indian Institute of Agricultural Biotechnology (IIAB-ICAR) & Botanical Society of Bengal |
Scholarship/Award/Felicitations
| Sl No. | Year/Month | Details of Awards |
|---|---|---|
| 1 | 2017 | CSIR-Research Associateship |
Any other Information
| Other Information |
|---|
| Governing body Member of Baguihati Deshbandhunagar Pather Pothik, a registered Non-Govt. Organization from 2022 onwards, working for education and healthcare of tiger widows and their children and trafficked women of Sundarban area, West Bengal., |